ENDOWORLD HOSPITAL # 723, In front of Airport, Chikalthana, Aurangabad – 431007, Maharashtra, India.
ICSI is intracytoplasmic sperm injection. Male infertility is mainly due to no sperms, low sperm counts, diminished motility and high percentage of abnormal sperm count. Intracytoplasmic Sperm Injection (ICSI) is the answer to tackle male infertility and failed fertilization in IVF. In ICSI, a direct injection of a single spermatozoon in a mature oocyte is carried out with help of micromanipulator under inverted microscopic guidence. Semen of male patients is washed and a single sperm, which is morphologically normal, is selected and injected in the oocyte with a very fine needle. Rests of the basic steps are similar to IVF.
(In patients with azoospermia due to vassal or epididymal blocks) When semen analysis shows absent sperms but testicular biopsy shows production of sperms in testes then various surgical sperm retrieval techniques are used to retrieve the sperms from testes or the collection system. ICSI treatment is done with these surgically retrieved sperms to achieve the pregnancy. These techniques are
Success rate of IVF-ICSI
The success of conception and pregnancy depends on causes of infertility in a couple, age of female partner, number and grade of embryos transferred, experience of treating doctors, IVF lab standard and many other factors. In our center, the rate of fertilization with ART is 90 to 100% with 45 to 55% pregnancy having attained with ICSI, practically over-ridding male factor. 45 to 55% is the current rate of pregnancy in our center with IVF -ICSI procedures. This success rate is comparable with worldwide success rate of IVF-ICSI. There is of course no specific age limit for couples who may be considered for IVF-ICSI in our center, but as per ICMR guidelines pregnancy is not advocated after the age of 50 years for female partner.
Following are the causes of failure of IVF-ICSI in infertile couple:
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